Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection

Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is greater than that of men. On the other hand, since the mother-to-child transmission route via the breast-feeding is common for baby boys and girls, it has been thought the HTLV-I proportions of boys and girls are the same until now. A question arises as to whether the "innate protection powers against human virus" are the same between baby boys and girls. We utilize Blood donors in 1995-1998, which were provided by Japan Red Cross Society of Oita, Japan. The data are summarized into the frequency table with respect to gender and age. The age groups are <20, 20<age≤30, 30<age≤40, 40<age≤50, and >50 years old. The comparison of carrier proportions of males and females under 20 years old is made with a two-sided statistical test and for the other groups one-sided tests are carried out. The preset statistical analysis shows that the carrier proportion of girls is less than that that of boys. It implies that in HTLV-I the mother-to-child transmission probability of females is less than that of males. According to the present findings, it follows that the female's innate protection power against HTLV-I is stronger than that of males, and the conclusion may become a valid proposition for general human virus

An annotated bibliography on the biology and fishery of the skipjack tuna, Katsuwonis pelamis, of the Pacific Ocean

ENGLISH: The skipjack tuna, Katsuwonus pelamis is an important resource of the tropical and subtropical waters of the world ocean. Fishermen of many countries exploit this resource; at the present time, the annual world catch is approximately 200 thousand metric tons. Many fishery experts believe that the skipjack is not being fully utilized while stocks of other tunas are being fished, in some areas, at levels exceeding their maximum sustainable yields. In addition to the importance of skipjack as a commercial fish and as a source of food, there is a small but expanding recreational fishery in some countries bordering the Pacific. This bibliography provides a list of publications pertaining to the biology and fishery of the Pacific skipjack tuna. Papers concerned with food technology, food chemistry, radio-chemistry, and certain other subjects are excluded. The main sources for our publication have been the existing bibliographies of tunas, which are listed and indexed accordingly. In addition, reports of various marine laboratories and other scientific organizations have been checked; these are too numerous to list. We are fairly confident that all major works pertaining to skipjack tuna in the Pacific, printed prior to the end of 1966, appear in this bibliography. Only reports considered to be in permanent form are included. Annotations are based on actual examination of each of the entries listed here. The annotations do not evaluate a paper but serve rather to give a more precise idea of its contents if not revealed by the title alone. If the title sufficed in this respect, no annotation was prepared. A relatively small number of works believed to contain information pertinent to our bibliography could not be examined, but a list of such papers is provided. SPANISH: El atún barrilete, Katsuwonus pelamis, es un recurso importante de las aguas tropicales y subtropicales del océano mundial. Los pescadores de varios países explotan este recurso; actualmente, la captura mundial anual es aproximadamente de 200,000 toneladas métricas. Muchos expertos en la pesquería creen que el barrilete no es utilizado completamente, mientras los stocks de otros atunes son pescados en algunas áreas a niveles que exceden su rendimiento máximo sostenible. Además de la importancia del barrilete como pez comercial y como fuente de alimento, existe una pesquería pequeña recreativa que se está desarrollando en algunos países colindantes con el Pacífico. Esta bibliografía suministra una lista de publicaciones correspondientes a la biología y pesquería del atún barrilete en el Pacífico. Estudios referentes a la tecnología alimenticia, química alimenticia, radioquímica y ciertos otros sujetos son excluídos. Las fuentes principales correspondientes a nuestra publicación han sido las bibliografías existentes sobre atunes, las cuales están enumeradas y catalogadas de acuerdo. Además, se han examinado los informes de varios laboratorios marítimos y los de otras organizaciones científicas; éstos son demasiado numerosos para enumerar. Estamos bastante seguros de que todos los trabajos principales correspondientes al atún barrilete del Pacífico, editados antes de terminar el año de 1966, aparecen en esta bibliografía. Se incluyen únicamente los informes que se consideran permanentes. Las anotaciones se basan en el examen actual de cada una de las entradas aquí referidas. Las anotaciones no evaluan un estudio, pero sirven más bien para dar una idea más precisa de su contenido si el título por sí mismo no lo explica. No se preparó ninguna anotación si el título a este respecto era suficiente. Un número relativamente pequeño de trabajos que se cree tengan información pertinente a nuestra bibliografía no pudo ser examinado, pero se suministra una lista de tales estudios. (PDF contains 227 pages.

Part-Paid Stock, Corporate Finance, and Investment: Economic Consequences of the Part-Paid Stock System and Supplementary Installments in the Early 1930s of Japan

Under Japanfs prewar capital stock system of joint-stock companies, rather than paying the full face value of a share in one lump sum, shareholders paid for stocks in multiple installments. This system was transplanted from industrialized Western nations during the Meiji Era to make it easier for investors to buy company shares and to promote capital concentrations. Company directors determined the amount of supplementary installments on part-paid stocks and when these installments were paid. The Commercial Code and Corporate articles of association specified sanctions for nonpayment, giving companies the backing needed to call in supplementary installments. Supplementary installments functioned as a last resort for corporate fund-raising in times of financial distress and played a role in corporate cash management and investment. Studies of historical documents such as financial statements and company histories show that in the early 1930s of the Great Depression, in a time of tight financial markets, many companies raised funds through supplementary installments, applying these funds to make investments and repay debts. As part of our study, we construct a new corporate financial data set with data on supplementary installments encompassing 174 firms, based on the Mitsubishi Economic Research Institutefs Honpo Jigyo-Seiseki Bunseki (Performance analysis of Japanese companies) and Toyo Keizaifs Kabushiki Gaisha Nenkan ( Company Year Book) and estimate cross-sectional investment functions for the fiscal year of 1932. Regression results suggest that while corporate investments were subject to liquidity and debt constraints, supplementary installments stabilized corporate cash management and promoted corporate investment activities.part-paid stock, joint-stock company, corporate finance, investment, financial system, interwar period, Great Depression

Wide-Field Survey of Emission-line Stars in IC 1396

We have made an extensive survey of emission-line stars in the IC 1396 HII region to investigate the low-mass population of pre-main sequence (PMS) stars. A total of 639 H-alpha emission-line stars were detected in an area of 4.2 deg^2 and their i'-photometry was measured. Their spatial distribution exhibits several aggregates near the elephant trunk globule (Rim A) and bright-rimmed clouds at the edge of the HII region (Rim B and SFO 37, 38, 39, 41), and near HD 206267, which is the main exciting star of the HII region. Based on the extinction estimated from the near-infrared (NIR) color-color diagram, we have selected pre-main sequence star candidates associated with IC 1396. The age and mass were derived from the extinction corrected color-magnitude diagram and theoretical pre-main sequence tracks. Most of our PMS candidates have ages of < 3 Myr and masses of 0.2-0.6 Mo. Although it appears that only a few stars were formed in the last 1 Myr in the east region of the exciting star, the age difference among subregions in our surveyed area is not clear from the statistical test. Our results may suggest that massive stars were born after the continuous formation of low-mass stars for 10 Myr. The birth of the exciting star could be the late stage of slow but contiguous star formation in the natal molecular cloud. It may have triggered to form many low-mass stars at the dense inhomogeneity in and around the HII region by a radiation-driven implosion.Comment: 48 pages, 12 figures, 5 tables, accepted for publication in A

Wheelchair half-marathon and marathon performance – the ‘Oita International Wheelchair Marathon’ 1983-2011

We compared participation and performance trends of individuals with disabilities competing in the half- and full-marathon in the ‘Oita International Wheelchair Marathon’ from 1981 to 2011. The performance times decreased during the 1980’s until the middle 1990’s and stabilized thereafter for both half-marathoners and marathoners. The mean top five overall finishers times were 0:52±0:07 h:min for half-marathoners and 1:36 ±0:11 h:min for marathoners, respectively. The mean age of the finishers increased significantly (p < 0.01) by 0.51 year per annum for the half-marathoners and by 0.62 year per annum for the marathoners, respectively. There was a significant (p < 0.001) age effect on time performance for both distances. The best time performance was observed for the age comprised between 16 and 54 years for half-marathoners, and between 25 and 49 years for marathoners, respectively

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese

The single nucleotide polymorphism (SNP) rs7566605 in the upstream region of the insulin-induced gene 2 (INSIG2) is associated with the obesity phenotype in many Caucasian populations. In Japanese, this association with the obesity phenotype is not clear. To investigate the relationship between rs7566605 and obesity in Japanese, we genotyped rs7566605 from severely obese subjects [n = 908, body mass index (BMI) ≥ 30 kg/m2] and normal-weight control subjects (n = 1495, BMI < 25 kg/m2). A case–control association analysis revealed that rs7566605 was significantly associated with obesity in Japanese. The P value in the minor allele recessive mode was 0.00020, and the odds ratio (OR) adjusted for gender and age was 1.61 [95% confidential interval (CI) = 1.24–2.09]. Obesity-associated phenotypes, which included the level of BMI, plasma glucose, hemoglobin A1c, total cholesterol, triglycerides, high-density lipoprotein (HDL) cholesterol, and blood pressure, were not associated with the rs7566605 genotype. Thus, rs7566605 in the upstream region of the INSIG2 gene was found to be associated with obesity, i.e., severe obesity, in Japanese

Reference values for the locomotive syndrome risk test quantifying mobility of 8681 adults aged 20–89 years: A cross-sectional nationwide study in Japan

Background The locomotive syndrome risk test was developed to quantify the decrease in mobility among adults, which could eventually lead to disability. The purpose of this study was to establish reference values for the locomotive syndrome risk test for adults and investigate the influence of age and sex. Methods We analyzed 8681 independent community dwellers (3607 men, 5074 women). Data pertaining to locomotive syndrome risk test (the two-step test, the stand-up test, and the 25-question geriatric locomotive function scale [GLFS-25]) scores were collected from seven administrative areas of Japan. Results The reference values of the three test scores were generated and all three test scores gradually decreased among young-to-middle-aged individuals and rapidly decreased in individuals aged over 60 years. The stand-up test score began decreasing significantly from the age of 30 years. The trajectories of decrease in the two-step test score with age was slightly different between men and women especially among the middle-aged individuals. The two physical test scores were more sensitive to aging than the self-reported test score. Conclusion The reference values generated in this study could be employed to determine whether an individual has mobility comparable to independent community dwellers of the same age and sex

Neural avalanches at the edge-of-chaos?

Does the brain operate at criticality, to optimize neural computation? Literature uses different fingerprints of criticality in neural networks, leaving the relationship between them mostly unclear. Here, we compare two specific signatures of criticality, and ask whether they refer to observables at the same critical point, or to two differing phase transitions. Using a recurrent spiking neural network, we demonstrate that avalanche criticality does not necessarily lie at edge-of-chaos